Chelate and complex preparations
Sukralfag (Venter); tablets, 0.5 g. The complex of aluminum hydroxide and sucrose octulphate, which has gastroprotective, antacid, adsorptive and enveloping properties. Indication: JBD, JBD, symptomatic and stress gastroduodenal ulceration, reflux esophagitis. Contraindications: children's age (up to 4 years), hypersensitivity, pregnancy,
Gastrointestinal bleeding, severe renal failure. Side effects: constipation, diarrhea, nausea, epigastric discomfort, dry mouth, rash, itching, headache, dizziness, drowsiness, back pain. Cautions: kidney failure, breast-feeding. Doses and application: inside by 1 tab. for 30-60 minutes before meals 3 times a day, 4 th time 2 hours after the last meal for 4-6 weeks (up to 12 weeks).
Fig. 9.5. Antacid selection algorithm
Means for the treatment of NSAID-gastropathy
Risk factors for NSAIDs-gastropathy: age over 60, history of peptic ulcer, high doses of PPVA, alcohol abuse, concomitant administration of glucocorticoids (GK) and anticoagulants. For the prevention of NSAID-gastroatia, patients with risk factors are shown: replacement of the drug with less ulcerogenic, administration of proton pump blockers in standard doses, misoprostol (400-800 micrograms per day) or H2-histaminoblockers in usual or doubled doses, antihelikobakternaya therapy. With developed NSAID-gastropathy, IIIIBC is abolished or H2-histaminoblockers are prescribed in usual or doubled doses, misoprostol (800 micrograms per day) or proton pump inhibitors in standard doses. Duration of treatment - 4-8 weeks.
Misoprostol (Saitotec) is a synthetic analogue of PGE. Dose-dependent suppresses basal and stimulated production of HC1, without having a significant effect on the concentration of serum gastrin. Has cytoprotective effect. In patients receiving NSAIDs, reduces the incidence of gastric ulcers (from 7-11 to 2-4%) and duodenal ulcers (from 4-9 to 0.2-1.4%), significantly reduces the risk of ulcer bleeding. In most patients it is possible to achieve healing of erosive-ulcerative lesions without the withdrawal of NSAIDs. Indication: prevention and treatment of NSAIDs-gastropathy. Contraindications: hypersensitivity, expressed violations of the liver, inflammatory bowel disease, pregnancy (pregnancy planning), breast-feeding. Side effects: diarrhea in 11-33% of patients, mild diarrhea is not considered a reason to stop treatment, with severe diarrhea drug is canceled. Flatulence, nausea, vomiting, skin rash, headache, dizziness, lower abdominal pain, spotting from the vagina. Cautions: hypotension, epilepsy, inflammatory bowel disease, damage to the arteries of the heart and brain, kidney failure, old age. To exclude pregnancy, treatment should be started no earlier than the 2nd-3rd day after menstruation.
Phytoprophylaxis of exacerbation of the disease
Taking phytopreparations is safer than using synthetic antiulcer drugs.
Ayr marsh ( Acorns calamus), the family. ( Asocracea ). Indications: peptic ulcer, jaundice, malaria, inflammation of the bladder, festering wounds, bad breath.
Barberry common ( Berberis vulgaris), the family. Barberry ( Berberidaceae ). Indications: chronic liver and gallbladder diseases, peptic ulcer and duodenal ulcer, upper respiratory tract diseases, uterine bleeding.
The immortelle is sandy, or cymine ( Helichrysum arenarium), the family. Compositae ( Compositae ). Indication: inflammation of the gallbladder, gastric mucosa with high acidity, liver and colon, gallstone disease.
Cowberry ordinary ( Vaccinium vitis -idaea ), the family. cowberry ( Vacciapiace ). Indications: urolithiasis, inflammation of the bladder, gastric mucosa with low acidity, arthritis of rheumatoid origin.
Three-leafed watch, or a shamrock ( Menyanthes trifoliate), family. watch ( Memjanthaceae ). Indications: gastritis with low acidity, constipation, flatulence, skin and mucous membrane ulcers.
Camel's common thorn ( Alhagi pseudalhagi), family. beans ( Leguminosae ). Indications: dysentery and its prevention, inflammation of the colon and gallbladder, peptic ulcer of the stomach and duodenum, indomitable cough, tonsillitis, pustular skin diseases.
Heather ordinary ( Saulip vulgari ), the family. heather ( Ericaceae ). Indications: rheumatism, tuberculosis, atherosclerosis, dry cough with hard-to-separate sputum, inflammation of the liver, spleen, bladder and gastric mucosa with high acidity, festering wounds.
Highlander bird, or litter ( Polygonum aviculare), family. buckwheat ( Polygospase ). Indications: chronic diseases of the urinary tract, inflammation of the intestinal mucosa, peptic ulcer of the stomach and duodenum, the initial stage of urolithiasis.
Devyasil high ( Inula helenium), the family. Compositae ( Compositae ). Indications: inflammation of the respiratory tract, cough with hard-to-separate sputum, stomach and gallbladder diseases, irregular menstruation, hemorrhoids, epilepsy, diabetes.
Dymyary officinalis ( Fumaria officinalis), family. fumigious ( Fumarioideae ). Indications: decreased secretion of gastric juice, putrefactive processes in the intestine, gallbladder disease, cholelithiasis and urolithiasis, bronchitis.
Hypericum perforatum ( Hypericum perforatum), the family. ( Hyperioideae ). Indication: peptic ulcer, diarrhea, gallbladder and bladder diseases, colonic and intestinal spasm, skin lesions, wound surfaces, ulcers, abscesses, burns.
Wild strawberry forest ( Fragaria vesca), family. Rosaceae ( Rosaceae ). Indications: inflammatory and ulcerative processes of the gastrointestinal tract, cholelithiasis and urolithiasis, colitis, salt metabolism, pigment spots, anemia.
A thousand-year-old gold bearer, or ordinary ( Centaurium erythraea), the family. gentian ( Gentianaceae ). Indications: gastritis with low acidity, liver, gallbladder and kidney disease, heartburn.
Calendula officinalis, Calendula officinalis), family. Compositae ( Compositae ). Indications: peptic ulcer of stomach and duodenum, inflammation of the small and large intestines, liver and gallbladder diseases, bruises, cuts, burns, furunculosis, cervical erosion, periodontal disease, gum bleeding.
Cabbage ( Brassica olerucea), the family. Cruciferous ( Cruciferae ). Indication: peptic ulcer of the stomach and duodenum, inflammation of the gastric mucosa, liver disease, spastic colitis.
Common potatoes ( Solanum tuberosum), the family. Solanaceous ( Solapaseae ). Indications: gastritis with high acidity, stomach ulcer, constipation, inflammation of the mucous membrane of the mouth and pharynx, burns, panaritium, non-healing wounds.
Belladonna ( Atropa belladonna), Seven. Solanaceae ( Solanaceae ). Indication: peptic ulcer of the stomach and duodenum, bile and urolithiasis, intestinal colic, smooth muscle spasm.
Myasthenia vulgaris ( Filipendula ulmaria), family. Rosaceae ( Rosaceae ). Indications: trophic ulcers of the lower extremities, wounds, burns, eczema, peptic ulcer of the stomach and duodenum, bronchial asthma, chronic cholecystitis, inflammation of the upper respiratory tract.
Spinelet erect, or kalgan ( Potentilla erecta), the family. Rosaceae ( Rosaceae ). Indication: diarrhea, gastric, intestinal and uterine bleeding, tonsillitis, skin diseases.
Seed flax ( Linum usitatissimum), family. Flax ( Linaceae ). Indications: bronchial diseases, gastritis, peptic ulcer and duodenal ulcer, chronic colitis, inflammation of the urinary bladder and kidneys.
Peppermint ( Mentha piperita), family. clear ( Lamiaceae ). Indications: neurosis, insomnia, angina pectoris, inflammation of the gallbladder and upper respiratory tract, gastritis with high acidity, bad breath, toothache.
Alder gray ( Alnus incana), the family. birch ( Betulaceae ). Indication: diarrhea, peptic ulcer and duodenal ulcer, burns, nosebleeds.
Great purification ( Sedum maximum), family. crustaceans ( Grassulaceae ). Indications: peptic ulcer of the stomach and duodenum, chronic liver and gallbladder diseases, pulmonary and cardiac failure, slow and poorly healing wounds, sinus inflammation, periodontitis.
Shepherd's bag ( Capsella bursa -pastoris ), the family. Cruciferous ( Cruciferae ). Indications: acute and chronic inflammatory bowel diseases, gastric and duodenal ulcer, liver and gall bladder diseases, hemorrhoids, metabolic disorders.
Creeping white ( Bryonia alba), family. pumpkin ( Cucurbitaceae ). Indications: peptic ulcer and duodenal ulcer, bronchitis, pneumonia and pleura, cough, edema on the basis of liver diseases, warts, pigment spots, chronic inflammation of the joints, sciatica, gout, wet diathesis, chronic trophic ulcers, lesion of the scalp.
Parsley garden ( Petroselinum crispum), the family. umbrella ( Umbelliferae ). Indications: kidney and heart diseases, accompanied by edema, kidney stone disease, bladder inflammation, digestive disorders, uterine bleeding, gastritis with low acidity, mosquito bites, bees, wasps.
Tansy common ( Tanacetum vulgare), the family. astroids ( Asteraceae ). Indications: diseases of the liver, bile and bladder, round worms, decreased acidity of gastric juice, sluggishly healing ulcers.
Peony evading, or marjin root ( Paeonia anomala), family. pion ( Paeoniaceae ). Indications: decreased acidity of gastric juice, nervous, cold and gastrointestinal diseases, inflammation of the upper respiratory tract, metabolic disorders.
Plantain large ( Plantago major), family. plantains ( Plantaginaceae ). Indications: spasm of smooth muscles of the stomach, gastritis, peptic ulcer of the stomach and duodenum with low acidity, it is difficult to heal wounds, ulcers, boils, burns.
Chamomile pharmacy, or medicinal ( Matricaria recutita), family. astroids ( Asteraceae ). Indications: chronic gastritis, colitis, uterine bleeding, cholecystitis, intestinal spasm, flatulence, hemorrhoids, inflammation of the oral mucosa.
Sorbus ordinary ( Sorbus aisiral ), the family. Rosaceae ( Rosaceae ). Indications: decreased acidity of gastric juice, anemia, hypertension, gallbladder inflammation.
Licorice is naked ( Glycyrrhiza glabra), the family. beans ( Leguminosae ). Indications: acute respiratory disease, inflammation of the lungs, pharynx, gastric mucosa with high acidity, peptic ulcer of the stomach and duodenum, inflammation of the bladder and nights, constipation, polyhydramnios during pregnancy.
Yarrow ( Achillea millefolium), the family. Compositae ( Compositae ). Indications: intestinal, pulmonary, hemorrhoidal and other bleeding, flatulence, gastritis with low acidity, peptic ulcer and duodenal ulcer, hypertension, menstruation, wounds.
Common humming ( Humulus lupulus), the family. hemp ( Cannabaceae ). Indications: neurosis, insomnia, gastric and duodenal ulcer, inflammation of the gastric mucosa, edema, thrombophlebitis, inflammation of the noces and bladder, acne, hair loss, diarrhea, menopause.
Cretaceous Icelandic, or Icelandic moss ( Cetraria islandica), family. Parmelian ( Parmeliaceae ). Indications: intestinal and pulmonary inflammatory diseases, flatulence, gastritis with low acidity, gastric ulcer and duodenal ulcer, wounds.
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